POS1077 CLINICAL AND RADIOLOGICAL FEATURES OF SEROPOSITIVE PSORIATIC ARTHRITIS

Background: Rheumatoid factor (RF) and anti-cyclic citrullinated peptides (anti-CCP) are two highly specific laboratory markers for rheumatoid arthritis. However, they can also be found in other chronic inflammatory arthritis such as psoriatic (Psa). Objectives: The aim of our study is to analyze the different epidemiological paraclinical characteristics seropositive Methods: Descriptive analytical retrospective from January 2010 December 2020 conducted Department Rheumatology University Hospital Ibn Rochd, Casablanca. Inclusion criteria: patients diagnosed with according CASPAR or ASAS 2009 criteria, regardless immunological status (RF/anti-CCP). were then divided into groups: (positive anti-CCP / positive RF) seronegative. A univariate was performed by jamovi version 1.2.27 Results: 80 enrolled. 22 (Group 1) 58 seronegative 2). In group 1, mean age 51.1 years (+/- 9.45). sex ratio M/F 0.29, onset 43.5 10.4), duration disease 9.55 +/- 8 years. All had skin involvement. Polyarticular involvement present all cases; axial 68.18% cases enthesitis cases. HLA B 27 negative. presence X-ray ultrasound bone erosions addition signs destruction 81.8% response treatment (corticosteroids NSAIDs DMARDs) partial 70.58%. 2, 50.7 15.8). 1.14, 37.4 16.5), 13.3 9.5). Skin 50% patients. cases, 67.24% 56.9% 57.14%. Conclusion: several studies linked deformities, dactylites radiological (1,2). series, seropositivity accompanied erosive nature destruction, well a tendency resistance treatment. References: [1]Kim KY, Lee YH. Anti-cyclic peptide antibody arthritis: meta-analysis its frequency association clinical features. Z Rheumatol. mai 2020;79(4):397-403. [2]Hagiwara S, Tsuboi H, Terasaki T, M, Toko Shimizu et al. Association features Modern Rheumatology. 3 mars 2020;30(2):365-72. Table 1. Comparison PsA Items Group 1 Seropositive (n=22) 2 Seronegative (n=58) p-value Age (years) +/-9.45 15.8 0.9 Sex 0.29 1.14 0.013 10.4 37.4+/- 16.5 0.123 (%) 100 50 0.009 Bone 81.1 56.9 <0.001 Response 70.58 51.14 Disclosure Interests: None declared.